Preparation and in vitro evaluation of ibuprofen spherical agglomerates
نویسندگان
چکیده
منابع مشابه
Preparation of acrylic-type derivative of ibuprofen and in vitro evaluation studies of its polymeric prodrugs
Acrylic-type polymeric systems having degradable ester bonds linked to ibuprofen were synthesized and evaluated as materials for drug delivery. Ibuprofen, as a non-steroidal anti-inflammatory drug, was linked to 2-hydroxyethyl methacrylate by activated ester methodology in one-pot procedure. The resulting methacrylic derivative of ibuprofen was copolymerized with 2-hydroxyethyl methacrylate and...
متن کاملpreparation of acrylic-type derivative of ibuprofen and in vitro evaluation studies of its polymeric prodrugs
acrylic-type polymeric systems having degradable ester bonds linked to ibuprofen were synthesized and evaluated as materials for drug delivery. ibuprofen, as a non-steroidal anti-inflammatory drug, was linked to 2-hydroxyethyl methacrylate by activated ester methodology in one-pot procedure. the resulting methacrylic derivative of ibuprofen was copolymerized with 2-hydroxyethyl methacrylate and...
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Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computati...
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ژورنال
عنوان ژورنال: The Turkish Journal of Pharmaceutical Sciences
سال: 2018
ISSN: 1304-530X
DOI: 10.4274/tjps.09609